The 2016 Rexall OneWalk to Conquer Cancer raised $6.5 million. Since 2003, supporters of The Princess Margaret have walked to help conquer cancer in all its forms. To date over $162 million has been raised. 2017 celebrates 15 years of walking to conquer cancer.
Funds raised through the Rexall OneWalk to Conquer Cancer support Personalized Cancer Medicine at The Princess Margaret, enabling world-leading clinicians and researchers to detect cancers earlier, diagnose with more precision, target treatment for each patient and support patients and their families throughout the cancer journey. Princess Margaret Cancer Centre is leading the way in Personalized Cancer Medicine as one of the top 5 cancer research centres in the world.
With OneWalk you choose to fundraise as a team or individually and you designate the fundraising dollars to support the cancer fund that matters most to you.
When a participant registers, they select a cancer fund to support, such as: Discovery Research, Breast, Gynaecologic, Lung, Gastrointestinal, Hepatobiliary, Genitourinary, Blood Cancers, Endocrine, Skin Cancer and Melanoma, Head and Neck Cancers, Central Nervous System Cancers, Brain and Eye Cancer, Sarcoma, Childhood Cancers, Supportive Care, Patient Education, and Radiation Medicine.
Princess Margaret Cancer Centre is one of the top 5 cancer research centres in the world. The Princess Margaret has the largest cancer research and clinical program in Canada. As global leaders in cancer care, The Princess Margaret has the expertise to treat over 200 types of cancers, including the rarest forms of the disease.
The Princess Margaret has a rich history of research excellence, discovery and innovation. Every day, oncologists at The Princess Margaret combine clinical strength with the research expertise of The Campbell Family Cancer Research Institute to deliver breakthrough cancer research, treatments and patient-centred care.
As Canada’s largest and most comprehensive cancer research centre, The Princess Margaret is responsible for delivering the evidence and measuring the benefit of new treatments and new approaches. The Princess Margaret is proud to lead the way in the creation and delivery of the new gold standard in cancer care: Personalized Cancer Medicine.
This new model of patient care will allow The Princess Margaret to detect cancer earlier, diagnose cancer with more precision, target treatment more effectively and support patients and families through their cancer journey. By leveraging research and clinical strength, The Princess Margaret will continue to lead the way and deliver the evidence that will create Personalized Cancer Medicine for patients at The Princess Margaret, across Canada and around the world.
The new discoveries and innovative cancer therapies that are changing cancer care for patients globally are happening right here in Canada, at The Princess Margaret.
The Princess Margaret is...
2014 2015 By the Numbers (approx average based on 5 day week):
Princess Margaret Cancer Centre treats over 200 types of cancer through surgery, chemotherapy, radiation, psychosocial and palliative care.
Funds raised since 2003 have powered a range of cancer research, clinical enhancements survivorship and other programs at Princess Margaret Cancer Centre.
*New cancer drug development is a long and risk-filled process. We are very encouraged by this discovery and reaching this major milestone. The drug discovery from Dr. Tak Mak and Dr. Dennis Slamon announced by The Princess Margaret Cancer Foundation in June 2013 has been cleared by Health Canada and the University Health Network Research Ethics Board, and is in clinical trials. For more information please visit www.canadiancancertrials.ca.
To achieve global impact, a scientific research institute requires world-class people, platforms and programs. The Campbell Family Cancer Research Institute at Princess Margaret Cancer Centre is fortunate that many top scientists have left their homes to come to Toronto because they believe that this is where they can have the most impact.
The Institute is building world-class research programs utilizing our expertise in the scientific platforms most vital for cancer research: mass spectrometry, flow cytometry, new drug discovery, genetic sequencing, biobanking and computational biology.
Breast cancer is the most common cause of cancer death in Canadian females, accounting for 13 per cent of all female cancer deaths. One in 9 Canadian women are expected to develop breast cancer in their lifetime and 1 in 30 will die from it.
In 2016, it is estimated that:
The most recent incidence statistics for other and unspecified female genital organ cancers are from 2010:
The most recent mortality statistics for other and unspecified female genital organ cancers are from 2012:
Colorectal and Gastrointestinal Cancers
26,100 Canadians will be diagnosed with colorectal cancer in 2016, representing approximately 13 per cent of all new cancer cases in 2016.
It is estimated that in 2016, 3,400 Canadians will be diagnosed with some form of stomach cancer.
Incidence rates of stomach cancer in Canada occur about 2.1 per cent per year in males and 1.0 per cent in females.
The five-year relative survival for stomach cancer is 25 per cent. This means that, on average, people diagnosed with stomach cancer are 25 per cent as likely to live 5 years (or more) after diagnosis as people in the general population who do not have cancer.
Prostate, Testicular, Bladder Kidney and Genitourinary Cancers
In 2016, 21,600 men will be diagnosed with prostate cancer. This represents 21 per cent of all new cancer cases in men in 2016. Also in this year, 4,000 men will die from prostate cancer. This represents 10 per cent of all cancer deaths in men in 2016.
Prostate cancer is the most common type of cancer among Canadian men, excluding non-melanoma skin cancer.
New cancer cases among older adolescents and young adults aged 1529 years old account for approximately 1.5 per cent of all new cancer cases. Thirteen per cent of cancers diagnosed in this age group are testicular.
It is estimated that in 2016:
It is estimated that in 2016, 6,400 Canadians will be diagnosed with kidney cancer.
Pancreatic cancer is the fourth leading cause of cancer death in both sexes accounting for 6 per cent of all cancer deaths.
For both females and males, five-year survival is lowest for pancreatic cancer (females 8 per cent, males 7 per cent).
Head and Neck - Brain, Central Nervous System, and Eye
Eye cancer is rare. Each year, approximately 370 Canadians are diagnosed with eye cancer:
Skin Cancer & Melanoma
It is estimated that in 2016, 6,800 Canadians will be diagnosed with melanoma.
In 2010, 135 Canadians died from endocrine system related cancers. Because these cancers are so rare, prognosis is not well known.
There are nearly 10,000 children living with cancer in Canada today and 1,500 Canadian children will be diagnosed with cancer in 2016. One in five children will not survive their cancer diagnosis.
Childhood cancer accounts for less than one per cent of all new cancer cases in Canada.
The three types of cancer that account for the majority of new cancer cases in children 014 years of age in Canada are:
The three types of cancer that account for the majority of cancer death in children 014 years of age in Canada are:
Childhood cancers remains the most common disease-related cause of death more than asthma, diabetes, cystic fibrosis and AIDS combined. It is second only to injury-related deaths among Canadian children.
According to Statistics Canada, in 2012, cancer was the leading cause of disease-related death in children under the age of 15 years. An average of 290 people in Canada between the ages of 15 and 29 die from cancer each year. Young men are more likely to die than young women in this age range.
Due to advances in cancer therapy treatments, 78 per cent of children will survive five years or more.
It is estimated that in 2016, 28,400 Canadians will be diagnosed with lung cancer.
More than half of soft tissue sarcomas begin in the arm or leg. In 2010, 1,165 Canadians were diagnosed with soft tissue sarcoma.
The Supportive Care Department at Princess Margaret Cancer Centre is an innovative global leader, supporting patients and families at all stages of the cancer trajectory. Through clinical care, research, education and international partnerships, we continue to pioneer new approaches for patients and caregivers as they cope with the impact of cancer.
With over 50 specialized staff working with each of The Princess Margaret oncology clinics, the program sees more than 2,000 patients a year. They treat physical and emotional symptoms, such as pain, depression and anxiety, and assist patients and their caregivers in managing the complexities of cancer and treatment. The program supports patients and their caregivers from the time of diagnosis, through survivorship, to the advanced stages of cancer.
Supportive Care aims to pursue continued growth and evolution in its three key areas:
As a global leader in patient education, The Princess Margaret offers programs that encourage and enable people with cancer, their caregivers and their families to become active participants in their cancer care. Providing an environment where patients and families feel safe to learn and ask questions is part of how we do this.
Through hospital-based services and online communities that promote self-management and improved quality of life in the hospital, at home and in the community, we help people, no matter where they are in their cancer experience, get the knowledge, skills and strategies they need to make informed decisions and healthy lifestyle choices—and cope with the many challenges that cancer brings.
We bring our expertise in health communication, adult education and theories of health behaviour change to all our Princess Margaret practitioners, working with them to develop educational resources, including patient-centred curricula, pamphlets and videos.
Our patient support includes:
Cancer is the leading cause of death in Canada and is responsible for 30 per cent of all deaths.
In 2016, an estimated 202,400 new cases of cancer and 78,800 cancer deaths will occur Canada.
Lung, breast, colorectal and prostate cancer are the most common types of cancer in Canada (excluding non-melanoma skin cancer). Based on 2016 estimates:
The Princess Margaret uses cutting-edge radiation technologies and has the capacity to treat over 8,000 patients every year. The Radiation Medicine Program at The Princess Margaret the largest of its kind in Canada and one of the largest in North America. A team of radiation oncologists, therapists, physicists and nurses support the assessment, planning, treatment and follow-up care for common, rare and complex forms of cancer. For more information about the Radiation Medicine Program at The Princess Margaret, click here.
Your support is one reason. As the 15th year of the walk approaches, we are reminded of the thousands and thousands of women and men, who just like you, have laced up their shoes, trained, and fundraised, to walk for the Princess Margaret Cancer Centre.
The funds you and others have raised is one of the major reasons that Princess Margaret Cancer Centre is one of the top 5 cancer research centres in the world. Many of our eminent researchers would not be working at the cancer centre if not for the tremendous philanthropic support that comes from our walkers, donors, volunteers and supporters.
We believe another big reason is the intense curiosity and tenacity of our scientists and clinician researchers who never stop asking WHY—as they work with each patient, with each tumor sample, and with each new therapy. While we can’t prove it scientifically yet, our theory is that our researchers have an extra ‘WHY gene’!
The research you are supporting is helping our scientists and clinicians to find the answers and translate these insights and discoveries into innovations in patient care for Canada and the world.
With the funds and the generosity of our community of supporters, we are now in the early days of delivering on our promise of Personalized Cancer Medicine.
In 2017, Rexall™ One Walk to Conquer Cancer™ is on Saturday September 9th. This year you get to choose your distance and your impact with our 3 options: the new 15 km Celebrity Circuit; the Walker Favourite 25 km walk; or the big and bold 40 km Celebrity Challenge!
In closing, WHY do cancer patients and their families and friends want to support the research taking place at The Princess Margaret? As our Creed states “We have the momentum. We have the talent. And we have the passion.” And we never stop asking WHY—because WHY is in our DNA.
Veteran Walkers, I ask you to keep Walking. You know the impact you have made, but our battle is not over yet. First time Walkers, get ready for a Walk that will change your life.
Now is the time for all of us to Walk together, because we can’t walk away.
Paul Alofs (14-year committed Walker)
President & CEO
The Princess Margaret Cancer Foundation
The 2017 Rexall™ One Walk to Conquer Cancer™ will be a historic point in the journey as this is the Walk’s 15th year. I remember like it was yesterday, the first Walk and the passion that I saw in all the walkers faces as I greeted them at the Finish Line. I was so grateful for all that they had done and the amazing funds that each walker raised to support the work at the Princess Margaret Cancer Centre.
In the last many years we have accomplished so much together.
For example, the Cancer Centre created the first in-hospital survivorship program which was originally for breast cancer patients, but subsequently was expanded so that all patients could take advantage of this support program.
My scientific discovery team and I began the long journey to find new targets over a decade ago, and today, we have several novel therapies that have moved into clinical trials. To accomplish this, we created a new Therapeutics Group within the Campbell Family Institute at the Princess Margaret Cancer Centre. One drug known as PLK 4 has completed Phase 1 trials and is moving into Phase 2. A second drug known as TTK is moving into Phase 1 trials. The road for new therapies and true breakthroughs take time and ongoing funding. We also have other discoveries in the pipeline and therapeutics under-development which we are hoping to further advance in 2017.
Another major accomplishment has been the creation of the Tumor Immunotherapy Program. Drs. Lillian Siu and Pam Ohashi are Co-Directors of this program. The walkers supported our discovery work in Immunotherapy from the beginning. Today, it is one of the biggest ideas of the past decade and we believe it has the potential to revolutionize cancer therapy. This could be the fourth pillar of cancer treatment in addition to surgery, radiation and chemotherapy. We now have over 180 active clinical trials underway including Canada’s first gene-engineered T-cell trial. The Princess Margaret, in part to Walker community, now boasts Canada’s most comprehensive immunotherapy program. This work could be effective on a number of different types of cancer and even some of the more difficult to treat today.
As we continue on our journey, know that progress is being made. We understand so much more today than when I started my career in the 70’s. We are in an amazing era of genomic discovery and uncovering insights that have eluded researchers in previous decades. We now know that there are many forms of cancer within the same type and that some forms of one cancer are more related to another form of cancer. We are discovering new cancer targets and from that new targeted therapies.
So I encourage you to Walk in the Rexall OneWalk to Conquer Cancer to allow me and my fellow researchers to continue our work. I share your passion and your dream that one day all cancers not be a disease that you die from, but a disease that can be controlled and that you live with.
The team at the Princess Margaret Cancer Centre is committed but we can’t do it alone.
I will see you on the 2017 Walk, please make sure to come up and introduce yourself!
My heartfelt thanks,
Dr. Tak Mak
Director, The Campbell Family Cancer Research Institute
Princess Margaret Cancer Centre
Conquering cancer in our lifetime is a bold vision, and one that will have a huge impact. More than 40 percent of Canadians will be diagnosed with some type of cancer, so it is vital that we develop more effective treatments and continue research that will lead to a new understanding of how the disease begins and spreads.
Today, thanks to research, over 50 percent of all cancer patients live ten years or more (in the 1970s, it was 25 percent). For some types of cancers—breast, prostate and many types of lymphoma and sarcoma—the long-term survival rates are 80 percent or higher. But for other types—lung, pancreatic and ovarian—the rates remain persistently low. That is because they are all different diseases and need specially-designed diagnostic and treatment approaches.
As one of the top 5 cancer research centres in the world, the scientists and clinicians at Princess Margaret Cancer Centre are creating tomorrow’s cancer treatment today—one disease at a time. They are conducting over 700 clinical studies of new treatment approaches, and they have a responsibility to share their success and their insight about the disease with other cancer specialists in Canada and the world. Our job is to ensure they have the equipment and the support to do their life-saving work.
At The Princess Margaret Cancer Foundation, we don’t shy away from bold visions that require big funding. In April 2012, we launched a bold BILLION DOLLAR CHALLENGE to raise the funds needed to create a new gold standard of cancer care: Personalized Cancer Medicine. We have now passed the halfway point in the challenge and have secured $576 million through philanthropy and research grants.
Personalized Cancer Medicine will include new diagnostic and treatment approaches that reflect the reality that each person’s cancer is unique and each cancer patient is a unique individual. There are already over 200 documented types of cancer, and even when two people have the same type, it varies in size, position and potential to spread. And each patient’s ability to tolerate treatment is different.
We all have a reason to support the BILLION DOLLAR CHALLENGE. Cancer will impact you or a family member, a friend or close colleague. Thank you to all of our donors who have contributed to the challenge so far. We still have a long way to go, but we know that so many share our vision of a world where cancer is controlled and prevented. We hope we can count on your continued support.
Chair, Board of Directors
At The Princess Margaret, we are excited to be leading a new integrated approach to cancer treatment called Personalized Cancer Medicine.
This approach will include using a patient’s genetic information to more precisely diagnose their cancer and tailor the most effective treatment for them.
But Personalized Cancer Medicine at The Princess Margaret is so much more. We have always focused on the individual needs of each patient and not just their disease.
That is why we have:
Our strong culture of innovation has made this cancer centre a world leader in cancer research and treatment, and with your financial support, we will lead the way in Personalized Cancer Medicine.
Dr. Mary Gospodarowicz, Medical Director
What is Personalized Cancer Medicine?
Over the past 50 years, our scientists and physicians have learned just how complex cancer is. Every patient and every patient’s cancer is unique.
There has been a clear understanding for some time that cancer is a very different disease depending on where it originates. So today lung cancer is treated in a different way than colon or kidney cancer, or leukemia.
But more recently, new technology and insight have allowed us to see that the disease is even more complex than that. There can be many forms of lung cancer or colon cancer, and a genetic analysis of a tumour may be required to confirm the specifics of each patient’s disease.
The Princess Margaret is one of the top 5 cancer research centres in the world with an outstanding reputation for breakthrough research, exemplary teaching and compassionate care.
We are two years into our Billion Dollar Challenge, which is a five-year initiative to help revolutionize cancer care. Over the next three years, The Princess Margaret will continue to be creating the blueprint, developing and implementing new procedures, and setting the gold standard for Personalized Cancer Medicine for all patients at The Princess Margaret, across Canada and around the world. In addition to genetic analysis of tumours, this new approach to cancer treatment encompasses four main themes:
Detecting cancer earlier
If cancer is detected at an early stage, the prognosis for a complete remission is much improved. Our research teams are working on many early detection initiatives, including:
Diagnosing with more precision
New equipment and procedures that determine the specific genetic mutations or changes that gave rise to a patient’s cancer are being tested at The Princess Margaret. This information will enable the experts to recommend the optimal combination of drug and other therapies for successfully treating each patient.
Targeting treatment for each patient
Improved surgical, radiation and drug treatments will target only the cancer and leave healthy tissue alone, minimizing toxic side effects. Our scientists and doctors are testing new treatments that can more effectively detect and eradicate cancer cells leading to more durable cures.
Supporting patients and families throughout their cancer journey
Being well-informed about their disease, the treatment they will receive and the side effects that can be expected gives patients and their families more confidence, reduces anxiety and leads to improved quality of life. Our award-winning survivorship, patient education and psychosocial support programs need to be expanded so that more patients can be empowered throughout their personal cancer journey.
Princess Margaret Cancer Centre is one of the top 5 cancer research centres in the world. We are the largest cancer research and clinical program in Canada. As global leaders in cancer care, we have the expertise to treat over 200 types of cancers, including the rarest forms of the disease. The Princess Margaret has a rich history of research excellence, discovery and innovation. Every day, we combine our clinical strength with the research expertise of The Campbell Family Cancer Research Institute to deliver breakthrough cancer research, treatments and patient-centered care.
Because we are Canada’s largest and most comprehensive cancer research centre, The Princess Margaret is responsible for delivering the evidence and measuring the benefit of new treatments and new approaches. We are proud to lead the way in the creation and delivery of the new gold standard in cancer care: Personalized Cancer Medicine.
The Princess Margaret is
The Princess Margaret offers comprehensive cancer care across 13 disease sites: Breast, Lung, Gastrointestinal, Gynecologic, Genitourinary, Head and Neck, Central Nervous System, Lymphoma, Sarcoma, Leukemia, Eye, Melanoma, Thyroid
2016 By the Numbers:
The Princess Margaret Cancer Centre has achieved an international reputation as a global leader in the fight against cancer and delivering Personalized Cancer Medicine. The Princess Margaret, one of the top 5 cancer research centres in the world, is a member of the University Health Network, which also includes Toronto General Hospital, Toronto Western Hospital and Toronto Rehabilitation Institute. All are research hospitals affiliated with the University of Toronto. www.theprincessmargaret.ca
The Campbell Family Cancer Research Institute is recognized as one of the top 5 cancer research facilities in the world as measured by its number of new discoveries, the quality of its research, its reputation and its overall impact on conquering cancer in our lifetime.
The Campbell Family Institute for Breast Cancer Research was launched in June 2004 thanks to an extraordinarily generous gift of $25 million from the late Audrey Campbell and her three daughters. In addition, Susan Grange donated $5 million to support the innovative work of Dr. David Jaffray in the area of image-guided radiation.
The Campbell Family Cancer Research Institute, supported by the significant and long-term commitment of the Campbell Family and The Walk, is an international powerhouse at the Princess Margaret Cancer Centre. The Campbell Family Cancer Research Institute leads the world in many of the most promising areas of cancer research such as tumour metabolism, cancer stem cells, cancer genomics, proteomics, informatics and molecular imaging/guided therapeutics. The Campbell Family Institute builds on the breast cancer research work of internationally recognized Dr. Tak Mak and his team to benefit all cancers.
The sustainable development of The Campbell Family Institute will depend on the close integration of people and resources, enabling maximum global impact in the fight against cancer.
The Campbell Family Cancer Research Institute capitalizes on the work of existing stars, such as Dr. Tak Mak (t-cell receptor discovery and more recent new cancer target discovery), Dr. John Dick (cancer stem cells) and Dr. Pam Oashi (immune therapy) and a long list of distinguished researchers, to accelerate the pace of cancer research, facilitating the translation of scientific advances into new life-saving therapies that will help us in our collective efforts to CONQUER CANCER IN OUR LIFETIME.
The vision of The Campbell Family Cancer Research Institute is to continue to be recognized as one of the top 5 cancer research centres in the world as measured by its number of new discoveries, the quality of its research, its reputation and its overall impact on conquering cancer.
For more information go to: www.campbellfamilyinstitute.ca
The Challenge is a 5-year initiative to secure $1 BILLION to create the new gold standard in cancer care: PERSONALIZED CANCER MEDICINE.
This new approach to cancer care involves finding the right treatment, for the right patient, at the right time. Our focus is to detect cancer earlier, diagnose with more precision, target treatment for each individual and support patients and their families through their cancer journey.
The Billion Dollar Challenge supports this ambitious goal. The Princess Margaret Cancer Foundation’s challenge is to raise $500 million through philanthropy over this period while our researchers are challenged to secure $500 million in research grants. We are tracking ahead of plan, but every donation, every Walker and every program counts as we seek to accomplish this goal.
We are enormously grateful to all those who support our vision of Personalized Cancer Medicine. To create and deliver this new model of cancer care, leaders at The Princess Margaret are recruiting scientists, clinicians and other experts to further strengthen our position in important areas such as epigenetics, clinical genomics, bio banking, computational biology, immune therapy and pathology.
The Billion Dollar Challenge will help ensure that Princess Margaret Cancer Centre remains one of the top 5 cancer research centres in the world and leads the way in new therapies to save more lives for patients at The Princess Margaret, across Canada and around the world.
Immunotherapy is rapidly gaining recognition for its potential to change the way we treat cancer and to join chemotherapy, radiation and surgery as a fourth pillar of cancer treatment.
Within the international scientific community, it has been long understood that the immune system has the ability to conquer cancer. We’re now at a point where this knowledge has started to become translated into treatment possibilities for cancer patients.
We have already seen numerous success stories of cancers fought and lives extended through immunotherapy.
This vital research is made possible in part by donations received from more than 62,000 participants who have Walked The Walk! Because of OneWalk, we are advancing cancer research.Learn more about the vital work being done at The Princess Margaret to revolutionize immunotherapy treatment by clicking here.
To read The Princess Margaret's Immunotherapy Magazine, click here.